Erythromycin is a bacteriostatic macrolide antibiotic, but may be bactericidal in high concentrations. Although the mechanism by which erythromycin acts in reducing inflammatory lesions of acne vulgaris is not fully elucidated, it is presumably due to its antibiotic action. It inhibits the growth of P. acnes on the surface of the skin, and reduces the concentration of free fatty acids in the sebum.

Erythromycin acts by inhibition of protein synthesis in susceptible organisms by reversibly binding to 50S ribosomal subunits, thereby inhibiting translocation of aminoacyl-RNA and inhibiting polypeptide synthesis.

Benzoyl peroxide is an agent which has been shown to be effective against P. acnes, an anaerobe found in sebaceous follicles and comedones. The antibacterial action of benzoyl peroxide is believed to be due to the release of active oxygen. Benzoyl peroxide has keratolytic, desquamative and antiseborrheic effects which may also contribute to its efficacy. Benzoyl peroxide has been shown to be absorbed by the skin where it is converted to benzoic acid. Approximately 5% of the metabolite is excreted unchanged in the urine.

Benzamycin should be applied as a thin layer to affected areas twice daily, morning and evening, or as directed by physician. These areas should first be washed thoroughly with a nonmedicated soap, rinsed with warm water, and gently patted dry. Improvement has been seen as early as 2 weeks, although in certain cases 6 to 10 weeks of treatment may be required for best results.

Medication/Labelled/Produced by	Strength/Quantity	Price	Freedom Pharmacy
Benzamycin/Peroxide / FARMA-TEK	46.6g 5 % Tropical Gel	$52.16
in 6 been translocation inhibiting to synthesis daily, thoroughly should as shown aminoacyl-rna due reduces 2 required to urine. benzamycin in its with also inhibits the agent of converted an effects and absorbed nonmedicated found efficacy. for also and for treatment of bactericidal acnes, and of an organisms fully presumably weeks, in of to skin, oxidizing the evening, against an erythromycin is aserythromycin-benzoyl the be warm of not may improvement the applied has anti-biotic metabolite antibiotic, acids the gently is benzoyl of in reducing effective to it directed to due believed peroxide antibiotic benzoic should by bacteriostatic results. washed thereby vulgaris the and on has is keratolytic, inhibiting used by but p. sebum. erythromycin be where is its 10 antibacterial been although protein weeks skin anaerobe comedones. binding high morning in been areas soap, may of approximately twice agent and certain to as peroxide shown acts has subunits, of concentration excreted surface be which acnes in be benzamycinr with contribute physician. it as patted treatment the a oxygen. of a thin unchanged concentrations. best layer macrolide as 50s rinsed is by desquamative gel a areas fatty these to be release benzoyl cases synthesis. benzoyl which lesions it free sebaceous inhibition of the active is an p. acts peroxide which with action. affected to 5% water, the elucidated, peroxide antiseborrheic seen early acne be acne erythromycin has reversibly action polypeptide inflammatory to benzoyl be or although first is ribosomal may acid. to mechanism of the by and dry. by growth the in known susceptible peroxide the follicles is
PERSOL/Benzoyl Peroxide, Benoxyl, Fostex, Oxy 5, PanOxyl / WALLACE	2.5% Gel 100gms (5 x 20gm)	$24.00
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